Healvet antibodies Combo, more comprehensive detection of antibody concentrations.

Many pet owners know to give their pets vaccination canine triple, cat triple, rabies and other vaccines, but seldom in the vaccination is completed to check the antibody titer of the pet, seldom know whether the vaccine is playing a role in the body of the pet, but also do not know the pet on the vicious infectious diseases have no ability to defend.

The good imported vaccines on the market, its immunity can not reach 100%, after vaccination by a variety of factors, there are also cases of immune failure. Therefore, it is very important to check the antibody titer after vaccination. In this article, you can learn about the importance of antibody testing in pets.

What are antibodies?

Antibodies are immunoglobulins produced by plasma cells differentiated from B-lymphocytes by the body's immune system in response to the stimulation of antigens, and can bind specifically to the corresponding antigen.Antibodies are substances produced by the body's immune system to fight against pathogenic infections.The level of antibodies is the only reliable indicator of the immunization effect of a vaccine.

The necessity of antibody testing

1. The fatality rate of pet infectious diseases is high, through the antibody test can know the defense ability of pets against malignant infectious diseases: the fatality rate of the common disease canine distemper reaches more than 80%, the fatality rate of canine poliovirus reaches more than 60%, and the fatality rate of feline distemper reaches 70%.Among them, canine distemper, fine small, feline distemper and so on are more common in China.

2. Zoonotic diseases are extremely harmful, antibody testing is to protect pets and protect themselves: toxoplasmosis and rabies are zoonotic diseases, toxoplasmosis causes pregnant women to miscarry, stillbirths, rabies death rate and rabies after the death rate of nearly 100%.

3. There are differences in individual immune responses to vaccines, and there are many factors for immunization failure: they can be affected by genetics, nutritional status, the environment, disease, the quality of the vaccine and maternal antibodies.

When do we need to do antibody testing?

1. Evaluation of the level of maternal antibody before the initial immunization of young pets, before booster immunization or when the immunization history is unknown: to detect the residue of maternal antibody in dogs and cats, to prevent maternal antibody from interfering with the immunization effect of the vaccine; to detect the level of the existing antibody, to determine the need for re-immunization, to avoid unnecessary vaccinations and vaccine reactions.

2. Evaluation of the effect of immunization: Antibody test is usually conducted 3 weeks after the last vaccination to evaluate the pet's immune function and clarify the immunization effect of the vaccine. Canine distemper and Tiny are especially important, and the antibody is directly and positively related to the ability to resist disease. If the vaccine immunity is not effective, supplemental immunization as early as possible to ensure that the vaccine works.

3. Before possible stress and lowered resistance: before surgery, before hospitalization, before traveling, boarding, long-distance transportation, and before the mother prepares for pregnancy, etc.

4. Evaluate the prognosis: after the infectious disease is cured, evaluate the prognosis.

Why does immunization fail?

1. Genetic factors: the strength of the immune response is controlled by genetics to a certain extent.2. Nutritional status: The nutritional status of the body, such as vitamin, trace element and amino acid deficiency, will cause the immune response to be weakened.

3. Environmental factors: high stocking density, hygiene, temperature, humidity and other stresses can affect the immune response.

4. Disease effects: Parasites, viruses (leukemia, AIDS), bacteria and other diseases can cause immunosuppression.5. Vaccines: quality, preservation and transportation, use (immunization procedures, vaccination methods, etc.), safety (virulence).6. Serotypes of pathogens: some pathogens have multiple serotypes and are weakly cross-protective (leptospirosis, cupripovirus, etc.).

7. Influence of maternal antibodies: weakly virulent vaccines have a greater influence

8. Interaction of pathogenic microorganisms: multivalent vaccines often have the effect of interfering with each other (viruses infected with similar receptors, there is competition, viruses infected with an immune response affecting the replication of another virus)

Q&A

1. Antibody tests are expensive, why don't I just get an extra vaccination?

Antibody levels are not visible to the naked eye and can only be known through testing. Repeated immunization within a short period of time may cause immune paralysis or immune tolerance, reducing the effect of immunization, which is counterproductive.

2. Why do pets get infected even though they pass the antibody test?

Antibody level reflects the strength of the pet's ability to resist disease, the antibody level passes, indicating that the pet's incidence is low, but does not mean that 100% does not develop disease. When pets are malnourished, have major diseases, or live in an environment that is heavily contaminated with pathogens, the antibody level will also be affected, leading to the development of pets.

3. Is it necessary to measure antibody levels in adult pets that are vaccinated regularly every year?
Before regular vaccination every year, we will test your pet first, and if the level is enough, you don't need to vaccinate again, so as to reduce the burden of immune organs and reduce the chance of sarcoma at the injection site. Before traveling during holidays, boarding, long-distance transportation, and before preparing for pregnancy, mother pets should be tested for antibodies to comprehensively assess the pet's resistance, so as to avoid illnesses caused by exposure to pathogens in the outside world.

4. Why is the antibody high when it has not been vaccinated?

There are three cases:

① Before the first vaccination for kittens/puppies: maternal antibody

② Adult cats/dogs, immunized within the last 3 years: 2016 WSAVA "Dog and Cat Immunization Guidelines" recommends that after successful first immunization, the interval between re-boosting immunization should not be less than 3 years, and the need for immunization should be decided after evaluating the antibody level. If it is clear that the dog/cat has been immunized within 3 years, and high level of antibody is detected, and there is no relevant symptom, then it is immunized and does not need supplemental vaccination.

③ Adult dogs/cats with unknown immunization history: previous vaccination; previous exposure to pathogens.