Canine and Feline Pancreatitis Combined Card, Strong and Accurate Diagnosis!

Healvet Canine and Feline Pancreatitis Combined Card:

Canine: cCRP+cPL

Feline: fSAA+fPL

Pancreatitis

Pancreatitis (pancreas) Pancreatitis can be divided into acute pancreatitis and chronic pancreatitis. Acute pancreatitis is an acute inflammation of the pancreas caused by pancreatic enzymes digesting the pancreas itself, and occurs mostly in obese dogs and cats.

Chronic pancreatitis is a recurrent or persistent inflammatory change in the pancreas that results in extensive fibrosis of the gland, reduction of parenchymal cells, and a decrease in exocrine function of the pancreas.

Etiology

Pancreatitis occurs more frequently as a result of improper feeding and is highly prevalent in adults through middle age, with a higher incidence in dogs than in cats, and a higher incidence in females than in males. Natural onset is mostly acute hemorrhagic pancreatitis. The etiology may be related to the following factors.

1. nutritional factors: high-fat foods;

2. obesity and physical inactivity;

3. Disease factors: When certain infectious diseases occur in dogs, pancreatitis becomes one of the necessary diseases. Hyperlipoproteinemia, hypothyroidism, diabetes mellitus, hypercalcemia, toxic diseases, hepatobiliary diseases, toxoplasmosis, infectious peritonitis, and widespread leukocyte deficiency are all related to this disease;

4. Susceptible breeds: Miniature Schnauzer, Miniature Poodle, Cocker Spaniel, Siamese cat;

Clinical symptoms

Dogs:

① Gastrointestinal symptoms: vomiting, abdominal pain (prayer position), especially after eating fatty food;

② Other non-specific symptoms: depression, weakness, loss of appetite, anorexia, dehydration;

Cats.

(i) Cat pancreatitis is more insidious and less characteristic than in dogs;

② nonspecific symptoms: lethargy, weakness, loss of appetite, anorexia, weight loss, dehydration;

Clinical diagnosis
1. Blood tests

There is no specificity in the diagnosis of pancreatitis, but it can show the physical condition of the sick pet.

2. Serum biochemical tests

It can be used to understand the disease process of pancreatitis to determine whether other organs have been involved, etc.

3. Imaging

It is sensitive and specific for the diagnosis of canine pancreatitis. It requires a high level of equipment and skill, and there is a great deal of variability.

4. Pancreatic biopsy

Biopsy of the pancreas is considered to be the most authoritative diagnostic method for pancreatitis. Although pancreatic lesions can sometimes be visualized by dissection, the size of the pancreas cannot be used as a basis for determining pancreatitis, and not all dogs are suitable for biopsy.

5. Pancreatic lipase test

Pancreatic lipase (PL) is an endopeptidase secreted by the pancreas, which is mainly secreted by pancreatic pancreatic cells. It is organ-specific and will not be interfered by exogenous pancreatic lipase, so it has high sensitivity and specificity, which is helpful for early diagnosis of pancreatitis as well as therapeutic monitoring and evaluation of the efficacy of treatment.

Summarization

The diagnosis of pancreatitis should not only depend on the laboratory results, but should also correctly analyze the symptoms, physical examination results, and predisposing factors of the animal, and carefully judge the causes of changes in the indicators and the results of imaging diagnosis. At present, pancreatic lipase is considered to have the highest sensitivity and specificity in the diagnosis of canine and feline pancreatitis, and is the most effective test for pancreatitis.

Canine and Feline Pancreatitis Combined Card:
The quantitative fluorescence assay is one of the most important methods for measuring canine and feline specific lipase. The Hyvette Canine and Feline Specific Lipase Fluorescence Immunoquantitative Test Duplex Card is characterized by simple operation, accurate detection, good specificity and high sensitivity.
It can help to confirm the diagnosis of pancreatitis at an early stage, and can continuously monitor the effect of pancreatitis treatment according to the change of detection concentration. At the same time with canine CRP and cat SAA test can be used to assess the severity of pancreatitis, can monitor the development process and prognosis of canine and cat pancreatitis.

Association between canine and feline specific lipase with canine CRP and feline SAA:

1. In clinical examination, when encountering highly suspected pancreatitis but not morbid dogs, their serum lipase levels are not in the abnormal range, so they need CRP, which is a highly sensitive and early elevated indicator, to assist diagnosis and treatment, so as not to delay the condition. At the same time, the level of cCRP can be used to judge the severity of pancreatitis, and long-term monitoring of CRP can visualize the development of pancreatitis and its prognosis.

2. When acute and chronic pancreatitis occurs in cats, the disease may be insidious and almost asymptomatic in the early stage, while SAA can appear 4-6 hours after inflammation occurs, and the elevation is large (10-1000 times of the basal value), which can sensitively indicate the inflammation; its half-life is about 10 hours, and the concentration will drop quickly if the inflammation is well controlled, so it can be used to verify the effect of treatment.